By M.D. Peter G. Bourne
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Additional resources for Acute Drug Abuse Emergencies. A Treatment Manual
F u r t h e r m o r e , in m e t h a d o n e m a i n t e n a n c e p a t i e n t s w h o present in c o m a , alcohol, b a r b i t u r a t e s , a n d / or tranquilizers are m o r e likely t o be t h e agent(s) responsible for t h e poisoning because such p a t i e n t s usually have a high degree of crosstolerance t o any n a r c o t i c as a c o n s e q u e n c e of daily, large doses of m e t h a d o n e . T o o v e r c o m e this tolerance and p r o d u c e c o m a , a massive dose of a n a r c o t i c w o u l d be necessary.
Cardiopulmonary resuscitation. X4iW/4, 193:678-679, 1965. ; and Genton, E. Methadoneinduced pulmonary edema. 218:882-883,1971. ; and Rose, J. The major medical complications of heroin ddáicXion. Ann Intern Med, 6 7 : 1 - 2 3 , 1967. V. Management of emergencies. XIV. Cardiac arrest. Ν Engl J Med, 275:35-39,1966. National Academy of Sciences, National Research Council. Cardiopulmonary resuscitation. X4M4, 198:372-379,1966. S. The clinical spectrum of heroin pulmonary Qá^m^. Arch Intern Med, 122:122-127, 1968.
Blood pressure usually r e s p o n d s t o correction of h y p o x i a a n d m o d e r a t e fluid r e p l a c e m e n t . Fluids should n o t be administered t o o vigorously, or p r o b l e m s with p u l m o n a r y congestion m a y ensue, since these p a t i e n t s are n o t fundamentally volume-depleted. 2. ACUTE At this p o i n t , available historical data should be gathered a n d t h e physical e x a m i n a t i o n p e r f o r m e d . Blood gases should be sent t o t h e l a b o r a t o r y , and an electrocardiogram a n d chest χ ray t a k e n .
Acute Drug Abuse Emergencies. A Treatment Manual by M.D. Peter G. Bourne