By F. Sherwood. Taylor

Show description

Read or Download A History of Industrial Chemistry PDF

Best toxicology books

Download PDF by Shayne Cox Gad: Preclinical Development Handbook: Toxicology

A transparent, straight forward source to steer you thru preclinical drug developmentFollowing this book's step by step tips, you could effectively begin and entire severe stages of preclinical drug improvement. The booklet serves as a basic,comprehensive connection with prioritizing and optimizing leads, toxicity, pharmacogenomics, modeling, and rules.

Download e-book for kindle: Anticancer Drug Toxicity: Prevention, Management, and by Hans-Peter Lipp

Containing the newest findings at the toxicity of a variety of chemotherapeutic brokers, this up to the moment reference bargains specialist analyses at the pharmacokinetic-pharmacodynamic and pharmacokinetic-toxicodynamic relationships of anticancer compounds. Anticancer Drug Toxicity ·explores healing drug tracking (TDM) as a style of maximizing the efficacy, and minimizing the risks, of chemotherapy ·presents an unlimited volume of scientific pharmacokinetic info on cytostatic medicinal drugs ·offers a entire class of toxicity styles linked to using cytotoxic medicinal drugs ·analyzes the pharmacokinetics of alkylating brokers, platinum compounds, anthracyclines, antimetabolites, semisynthetic podophyllotoxin- and camptothecin derivatives, mitotic inhibitors, and different cytotoxic brokers ·highlights the pharmacogenetics of 6-mercaptopurine and its medical importance ·explicates toxicity in terms of the lungs, kidneys, middle, and gonads ·examines problems because of asparaginase arrangements ·reviews sorts of secondary malignancy akin to leukemias, ovarian melanoma, testicular melanoma, breast melanoma, secondary reliable neoplasias, and Hodgkin's illness ·clarifies the certainty of toxicity as an important aspect in supportive administration of melanoma remedy ·and extra!

New PDF release: Basic and Clinical Pharmacology 12/E

The main up to date, entire, and authoritative pharmacology textual content in future health medication greater by means of greater than 300 illustrations -- many in complete colour equipped to mirror the syllabi in lots of pharmacology classes and in built-in curricula, simple & medical Pharmacology, 12e covers the $64000 strategies scholars want to know concerning the technology of pharmacology and its program to scientific perform.

Download e-book for iPad: Polymers for Controlled Drug Delivery by Peter J. Tarcha

Polymers for managed Drug supply addresses the demanding situations of designing macromolecules that carry healing brokers that functionality properly and in live performance with dwelling organisms. The e-book basically discusses periods of polymers and polymeric cars, together with particulates, akin to latexes, coacervates, ion-exchange resins, and liposomes, in addition to non-particulate cars comparable to enteric coatings, mediators, and bioadhesives.

Extra resources for A History of Industrial Chemistry

Example text

F. (1992). Characterization of a rabbit gene encoding a clofibrate-inducible fatty acid o-hydroxylase: CYP4A6. Arch. Biochem. Biophys. 296, 66-72. Nebert, D. W. (1989). The Ah locus: Genetic differences in toxicity, cancer, mutation, and birth defects. Crit. Rev. Toxicol. 20, 153-174. Nelson, D. , Waxman, D. , Guengerich, F. , Estabrook, R. , Gonzalez, F. , Coon, M. , Gunsalus, I. , and Nebert, D. W. The P450 superfamily: Update on new sequences, gene mapping, accession numbers, early trivial names of enzymes, and nomenclature.

1992). The human hepatic cytochromes P450 involved in drug metabolism. Crit. Rev. Toxicol. 22, 1-21. , Hammons, G. , Martin, M. , Hopkins, N. , Alworth, W. , and Guengerich, F. P. Modification of cytochrome P450 1A2 enzymes by the mechanism-based inactivator 2-ethynylnaphthalene and the photoaffinity label 4azidobiphenyl. Biochemistry 31, 10556-10563. , Okerholm, R. , and Guengerich, F. P. Oxidation of the antihistaminic drug terfenadine in human liver microsomes: Role of cytochrome P450 3A(4)in Ndealkylation and C-hydroxylation.

Wolf, C . , Lennard, M. , and Sternberg, M. J. E. A three-dimensional molecular template for substrates of human cytochrome P450 involved in debrisoquine 4-hydroxylation. Carcinogenesis (London) 12, 221 1-2219. , and Schmidt, D. (1974). Anti-epileptic drugs and failure of oral contraceptives. Lancet 1, 1113. , Dahl, M. , and Ingelman-Sundberg, M. (1993). Inherited amplification of an active gene in the cytochrome P450 CYP2D locus as a cause of ultrarapid metabolism of debrisoquine. Proc. Natl.

Download PDF sample

A History of Industrial Chemistry by F. Sherwood. Taylor

by Michael

Rated 4.07 of 5 – based on 21 votes