By National Research Council, Division on Earth and Life Studies, Board on Environmental Studies and Toxicology, Board on Chemical Sciences and Technology, Committee on the Design and Evaluation of Safer Chemical Substitutions: A Framework to Inform Governme
Traditionally, laws governing chemical use have usually eager about well-known chemical compounds and acute human future health results of publicity to them, in addition to their power to reason melanoma and different opposed well-being results. As medical wisdom has extended there was an elevated information of the mechanisms wherein chemical substances could exert damaging results on human wellbeing and fitness, in addition to their results on other species and ecosystems. identity of high-priority chemical compounds and different chemical substances of outrage has brought on increasingly more kingdom and native governments, in addition to significant businesses, to take steps past latest detrimental chemical federal laws. curiosity in techniques and guidelines that make sure that any new ingredients substituted for chemical substances of outrage are assessed as rigorously and punctiliously as attainable has additionally burgeoned. The overarching aim of those methods is to prevent regrettable substitutions, which happen whilst a poisonous chemical is changed by way of one other chemical that later proved improper due to endurance, bioaccumulation, toxicity, or different matters. Chemical substitute exams are instruments designed to facilitate attention of those components to help stakeholders in picking chemical compounds that could have the best chance of injury to human and ecological healthiness, and to supply information on how the may perhaps improve and undertake more secure choices. A Framework to steer collection of Chemical choices develops and demonstrates a call framework for comparing in all likelihood more secure alternative chemical compounds as essentially decided by way of human wellbeing and fitness and ecological dangers. This new framework is expert by way of past efforts by means of regulatory organisations, educational associations, and others to advance replacement evaluation frameworks that may be operationalized. as well as danger checks, the framework contains steps for life-cycle considering - which considers attainable affects of a chemical in any respect levels together with construction, use, and disposal - in addition to steps for functionality and financial checks. The file additionally highlights how sleek details assets reminiscent of computational modeling can complement conventional toxicology facts within the evaluate method. This new framework permits the review of the whole variety of advantages and shortcomings of substitutes, and exam of tradeoffs among those dangers and components equivalent to product performance, product efficacy, technique defense, and source use. via case experiences, this record demonstrates how various clients in contrasting choice contexts with varied priorities can practice the framework. This document should be a vital source to the chemical undefined, environmentalists, ecologists, and country and native governments. Read more...
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Extra info for A framework to guide selection of chemical alternatives
In 2005, the Massachusetts state legislature requested that TURI evaluate alternatives to five chemicals of concern. TURI’s Alternatives Assessment Process Guidance (TURI 2006a) is an outgrowth of the resulting Five Chemicals Alternatives Assessment Study (TURI 2006b). The objective of the guidance document was to define a consistent process for setting priorities, 19 studying and evaluating the alternatives for the five chemicals (lead, formaldehyde, perchloroethylene, hexavalent chromium, and di (2-ethylhexyl) phthalate [DEHP]) (TURI 2006a).
Although changes to materials or designs might also provide alternatives to chemicals of concern, the framework does not focus on this option. Certain activities, although important to evaluating alternatives, were deemed to be beyond the scope of the current project. The committee provides sufficient information for an understanding of the general approach, but if more information is needed, the references supplied should be used. Those topics that may warrant more information include criteria and approaches for identifying and prioritizing chemicals of concern, a full discussion of life cycle analysis (LCA) practice, and detailed guidance on conducting performance, economic, or social impact assessments.
IC2, BizNGO, and the German Guide evaluate whether life cycle concerns indicate a need for a more formal life cycle assessment. Additionally, three other frameworks (CA SCP, REACH, and MCDA) suggest or consider factors, such as greenhouse gas emissions, that would normally be addressed through a life cycle assessment. The committee’s framework uses Life Cycle Thinking to complete this analysis. Life Cycle Thinking is also used to determine whether a more detailed evaluation of social impact is needed to inform a substitution decision.
A framework to guide selection of chemical alternatives by National Research Council, Division on Earth and Life Studies, Board on Environmental Studies and Toxicology, Board on Chemical Sciences and Technology, Committee on the Design and Evaluation of Safer Chemical Substitutions: A Framework to Inform Governme